How do I seperate myself from my cheating bipolar wife?

My wife had an affair in August ~ November 2006. I helped her through therapy from December 06 ~ February 07 before I was able to rekindle the marriage. I told her during marriage counseling in Feb 07, we should expect open communication and complete honesty in our relationship no matter how much it would hurt the other spouse. Everything seemed fine until November 07, then she started to become more isolated. I suspected something was not right, but could not approach her without evidence. I found out last Sunday was having an affair with the same person. The only thing keeping me from booting her out the front door is our 2 beautiful daughters. Her condition has nearly cost both of us our jobs. I feel I am at the end of the line. Please provide me some advice?

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